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[16] [18] Animal studies have not demonstrated teratogenicity, but high doses in pregnancy may theoretically increase the risk of fetal oxalate nephropathy or other metabolic disturbances

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10.1016/j.colsurfb.2016.06.053 Colloids Surf B Biointerfaces

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None of these windows is a clinical dosing instruction they describe how the compound is scheduled in research

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Supplementary Figure 6 (A, B) Cumulative data showing relative concentrations of decreased metabolites in the A vs HC group

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Case studies have also reported that direct antagonism of proinflammatory cytokines in patients with symptomatic SFN was associated with significant and sustained improvement in neuropathic symptoms, including dysautonomia (20), as well as with cognitive function and fatigue (18,21)

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